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If manufacturers want flavors like these approved, they would have to show the agency that those flavors are both more likely to get adult smokers to switch over to e-cigarettes than tobacco flavors, and that the benefits to adults “outweigh the added risk to youth.” “If the FDA imposes a high bar for evidence, that could be a difficult needle to thread,” Benjamin Chaffee, a professor at the University of California San Francisco Center for Tobacco Control, Research, and Education, said via email